About AST

Jacqueline G. O’Leary, MD MPH

Speciality: 
Hepatology
Graduated From: 
Stanford (undergraduate), UCSF (medical school), UTSW (residency), MGH (GI and Transplant Hepatology Fellowships), Harvard School of Public Health (MPH)
Current Position: 
Medical Director of Research, Baylor Simmons Transplant Institute, Baylor University Medical Center Medical Director of Hepatology Research, Texas Digestive Disease Consultants
Current Projects: 
D-SALT (Donor-Specific Antibodies in Liver Transplant) is a prospective multicenter investigator initiated trial evaluating the effects of DSA in Liver and SLKT recipients. We also have numerous retrospective pathology projects ongoing with Dr Jake Demetris from UPMC to further understand the role of DSA in Liver and SLKT recipients. I also enjoy being on the Steering committee of NACSLED (North-American Consortium for the Study of End-Stage Liver Disease), a multinational prospective effort to better understand infections in cirrhosis that is also a funded investigator initiated trial. As the Medical Director of Hepatlogy Research for Texas Digestive Disease Consultants we are actively enrolling patients from 70 unified private practice GI doctors all on one medical record into mostly pharma funded clinical trials. 
What made you decide to work in transplantation?: 
I originally was interested in oncology but hated that patients with end stage malignancy had no real treatment options. I loved hepatology because when patients became critically ill transplant would miraculously bring them back to life. As a transplant hepatologist we also get the opportunity to do fun procedures (I love to band varices!), use exciting new therapeutics (HCV treatment has been transformative), and enjoy getting to know patients and families doing long-term care. 
What do you find to be the most valuable aspect of your work?: 

Discovering new things about immunology. The immune system is incredibly complex and exciting, and I feel frequently humbled by how much we still have to learn.

Fun Facts: 

I love to ski with my family. Our daughter Diana just turned 7 and she loves to ski as much as I do.