Basic science

AST Journal Club on "Tregs integrate native and CAR-mediated costimulatory signals..."

AST Journal Club on "Tregs integrate native and CAR-mediated costimulatory signals..."

"Tregs integrate native and CAR-mediated costimulatory signals for control of allograft rejection"
- JCI Insight. 2023 Oct 9;8(19):e167215. doi: 10.1172/jci.insight.167215.
- Scheduled for Tuesday, February 27th from 2:00 PM ET to 3:00 PM ET
- Hosted by AST's Community of Transplant Scientists (COTS)

Speaker:
Isaac Rosado-Sánchez, PhD • University of British Columbia, BC Children’s Hospital Research Institute, Vancouver, BC

Moderator:
- Scott Krummey, MD, PhD • Johns Hopkins University School of Medicine, Baltimore, MD

Learn more at: https://www.myast.org/education/astajt-journal-club/tregs-integrate...

 

Tregs integrate native and CAR-mediated costimulatory signals for control of allograft rejection

Webinar: Maximizing the Gift: Post-organ Heart for Valves

Webinar: Maximizing the Gift: Post-organ Heart for Valves

 

This presentation has been developed in partnership with the American Association of Tissue Banks (AATB) and the American Society for Transplant Surgeons.

Donated heart valves can replace damaged valves or correct a congenital defect, allowing the heart to function normally. Heart for valves can be donated on shared organ and tissue cases when the heart is not recovered for transplant.

In this webinar, we will review common uses and criteria for donated heart for valves and how surgeons can preserve the opportunity for heart for valve donation during organ recovery.

Date: June 13, 2023, at 2:00 PM EDT

Registration Link: https://attendee.gotowebinar.com/register/4277163334361689181

Speakers: Bryan A. Whitson, MD, PhD

Professor of Surgery at Ohio State University

Bryan A. Whitson, MD, PhD is a Professor of Surgery at Ohio State University specializing in thoracic transplant, mechanical circulatory support, and adult cardiac surgery. He directs the Section of Thoracic Transplantation and Mechanical Circulatory Support. Additionally, he serves as the Interim Co-Director of The Ohio State University Heart and Vascular Center, Vice-Chair for Innovation and Translational Research, and the Jewel and Frank Benson Family Research Professor. Dr. Whitson has an active extramurally funded research lab and interacts with clinical house staff on the wards, in the OR, and on research projects regularly. 

Dr. Whitson completed his general surgery, surgical infectious diseases, and cardiothoracic surgery training at the University of Minnesota. His clinical and research interests include lung and heart transplantation, ex vivo organ perfusion, ECLS/ECMO, and mechanical circulatory support. He initiated the lung transplantation program at The Ohio State University in close collaboration with his pulmonary colleagues. He has spearheaded the development of the Organ Assessment and Repair Center (ARC) at OSU.

Additionally, Dr. Whitson co-directs The Collaboration for Organ Perfusion, Protection, Engineering, and Regeneration (COPPER) Laboratory at Ohio State, which brings together transplant surgery, endothelial cell biology, and biomedical engineering experts to further organ perfusion and recovery research. Dr. Whitson has 30 United States and international patents, numerous grants, and over 250 publications. He has three times been awarded the Thomas E Williams, Jr., MD, PhD Award for Excellence in Teaching from the OSU house staff and seven times received the Outstanding Achievement in Patient Service recognition from the OSU medical center.

Steve Julian, MD, MBA, CTBS

Associate Medical Director, LifeNet Health

Steve Julian, MD, MBA, CTBS is currently an Associate Medical Director with LifeNet Health in Virginia Beach, VA, and a participant in the AATB Physicians Council. He was previously a district director with the Virginia Department of Health, a physician administrator with Sentara Healthcare of Norfolk, VA, and a cardiothoracic and vascular surgeon with CV Surgical Associates in Salisbury, MD. Residency training occurred at Wake Forest University Medical Center in North Carolina, and during that time, he was involved with LifeNet in the development of techniques for heart valve recovery. He is a graduate of the Virginia Commonwealth University School of Medicine and Virginia Tech. He enjoys golf, bicycling, and being with family in his time away.

T3 Webinar: Microbiome in Transplantation

T3 Webinar: Microbiome in Transplantation

Microbiome in Transplantation
Wednesday, May 24, 2023, from 1:00 pm to 2:00 pm EDT

Speakers:
- Peter Mannon, MD, MPH • Professor of Medicine, Chief Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE
- Jonathan Bromberg, MD, PhD • Professor of Surgery and Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD

Moderator:
- Anoma Nellore, MD, FAST • Associate Professor of Medicine - Infectious Diseases, University of Alabama Birmingham, Birmingham, AL

 

he AST Education Committee would like to thank the Community of Transplant Scientists (COTS) and the Liver and Intestinal Community of Practice (LICOP) for suggesting this topic as part of the 2022-2023 T3 webinar series.

AST Journal Club on Kidney & Early Allograft Inflammation

AST Journal Club on Kidney & Early Allograft Inflammation

AST Journal Club on:
"Blocking CCL8-CCR8-Mediated Early Allograft Inflammation Improves Kidney Transplant Function"
Thursday, April 6th, 2023, from 2:00 PM ET to 3:00 PM ET • Hosted by AST's Community of Transplant Scientists (COTS)

Speaker:
- Xunrong Luo, MD, PhD, FAST • Duke University, Durham, NC

Moderator:
- Andrew Wells, PhD • University of Pennsylvania, Philadelphia, PA

All AST Journal Clubs, and featured AST/AJT Journal Clubs, are free but registration is required to attend live.

Blocking CCL8-CCR8–Mediated Early Allograft Inflammation Improves Kidney Transplant Function

Blocking CCL8-CCR8–Mediated Early Allograft Inflammation Improves Kidney Transplant Function

Thursday, April 6th, 2023, from 2:00 PM ET to 3:00 PM ET • Hosted by AST's Community of Transplant Scientists (COTS)

"Blocking CCL8-CCR8-Mediated Early Allograft Inflammation Improves Kidney Transplant Function"
(J Am Soc Nephrol. 2022 Oct;33(10):1876-1890. doi: 10.1681/ASN.2022020139. Epub 2022 Aug 16.)

Watch Video

Host-versus-commensal immune responses participate in the rejection of colonized solid organ transplants

Host-versus-commensal immune responses participate in the rejection of colonized solid organ transplants

Recorded live on Thursday, January 19th, 2023, from 2:00 PM ET to 3:00 PM ET • Hosted by AST's Community of Transplant Scientists (COTS)

"Host-versus-commensal immune responses participate in the rejection of colonized solid organ transplants"
(J Clin Invest. 2022 Sep 1;132(17):e153403. doi: 10.1172/JCI153403.)

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AST/AJT Journal Club on "NFAT-dependent and -independent exhaustion circuits..."

AST/AJT Journal Club on "NFAT-dependent and -independent exhaustion circuits..."

"NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy"
(J Exp Med. 2022 Jan 3;219(1):e20201599. doi: 10.1084/jem.20201599. Epub 2021 Dec 9.)

Tuesday, July 19, 2022, from 2:00 PM ET to 3:00 PM ET • Hosted by AST's Community of Transplant Scientists (COTS)

Speaker:
- Paige Porrett, MD, PhD • University of Alabama at Birmingham, Birmingham, AL

Moderators:
- Amandeep Bajwa, PhD • University of Tennessee Health Science Center, Memphis, TN
- Andrew Wells, PhD • University of Pennsylvania, Philadelphia, PA

AST/AJT Journal Clubs are free, but registration is required.

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy

Tuesday, July 19, 2022, from 2:00 PM ET to 3:00 PM ET • Hosted by AST's Community of Transplant Scientists (COTS)

"NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy"
(J Exp Med. 2022 Jan 3;219(1):e20201599. doi: 10.1084/jem.20201599. Epub 2021 Dec 9.)

Watch Video

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