Pediatrics

AST Journal Club: Machine learning-based prediction of health outcomes...

AST Journal Club: Machine learning-based prediction of health outcomes...

"Machine learning–based prediction of health outcomes in pediatric organ transplantation recipients"
(JAMIA Open. 2021 Mar 12;4(1):ooab008. doi: 10.1093/jamiaopen/ooab008. eCollection 2021 Jan.)

Wednesday, May 10th, 2023, from 4:00 PM ET to 5:00 PM ET • Co-sponsored by AST's Psychosocial and Ethics Community of Practice (PSECOP) and Pediatrics Community of Practice (PCOP)

Speaker:
- Michael Killian, PhD, MSW • Florida State University College of Social Work, Tallahassee, FL

Moderator:
- Ashley Spann, MD, MS Applied Clinical Informatics • Vanderbilt University Medical Center, Nashville, TN

All AST Journal Clubs, and featured AST/AJT Journal Clubs, are free but registration is required to attend live.

Machine learning-based prediction of health outcomes in pediatric organ transplantation recipients

Machine learning-based prediction of health outcomes in pediatric organ transplantation recipients

Wednesday, May 10th, 2023, from 4:00 PM ET to 5:00 PM ET • Co-sponsored by AST's Psychosocial and Ethics Community of Practice (PSECOP) and Pediatrics Community of Practice (PCOP)

"Machine learning–based prediction of health outcomes in pediatric organ transplantation recipients"
(JAMIA Open. 2021 Mar 12;4(1):ooab008. doi: 10.1093/jamiaopen/ooab008. eCollection 2021 Jan.)

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AST/AJT Journal Club: ""Three‐year outcomes from the CRADLE study..."

AST/AJT Journal Club: ""Three‐year outcomes from the CRADLE study..."

Recorded live on Thursday, October 1, 2020 • Hosted jointly by the TxPharm & Pediatric Communities of Practice

"Three‐year outcomes from the CRADLE study in de novo pediatric kidney transplant recipients receiving everolimus with reduced tacrolimus and early steroid withdrawal."
(Am J Transplant . 2020 May 14. doi: 10.1111/ajt.16005.)

In this article:
CRADLE was a 36‐month multicenter study in pediatric (1-to-18 years) kidney transplant recipients randomized at 4 to 6 weeks posttransplant to receive everolimus + reduced‐exposure tacrolimus (EVR + rTAC; n = 52) with corticosteroid withdrawal at 6‐month posttransplant or continue mycophenolate mofetil + standard‐exposure TAC (MMF + sTAC; n = 54) with corticosteroids... The overall incidence of adverse events (AEs) and serious AEs was comparable between groups. Rejection was the leading AE for study drug discontinuation in the EVR + rTAC group. In conclusion, though AE‐related study drug discontinuation was higher, an EVR + rTAC regimen represents an alternative treatment option that enables withdrawal of steroids as well as reduction of CNIs for pediatric kidney transplant recipients. (ClinicalTrials.gov: NCT01544491)

Speakers:
Robert Ettenger, MD • David Geffen School of Medicine at UCLA, Los Angeles, CA
Nicole Hayde, MD, MS • Albert Einstein College of Medicine, New York, NY

Moderator:
Justin Chen, PharmD • New York-Presbyterian Hospital, New York, NY

"Three-year outcomes from the CRADLE study in de novo pediatric kidney transplant recipients receiving everolimus with reduced tacrolimus and early steroid withdrawal"

"Three-year outcomes from the CRADLE study in de novo pediatric kidney transplant recipients receiving everolimus with reduced tacrolimus and early steroid withdrawal"

Recorded live on Thursday, October 1, 2020 • Hosted jointly by the TxPharm & Pediatric Communities of Practice

"Three‐year outcomes from the CRADLE study in de novo pediatric kidney transplant recipients receiving everolimus with reduced tacrolimus and early steroid withdrawal."
(Am J Transplant . 2020 May 14. doi: 10.1111/ajt.16005.)

Watch Video

T3 Webinar: "Sexual Health and Monitoring Recommendations for Transplant Recipients"

T3 Webinar: "Sexual Health and Monitoring Recommendations for Transplant Recipients"

Speakers:
Lisa Coscia, RN, BSN, CCTC • Transplant Pregnancy Registry, Philadelphia, PA
Monica Ardura, DO, MSCS • Nationwide Children's Hospital, Columbus, OH

Moderator:
Melissa Meyers, MD, MSCE • Rainbow Babies and Children's Hospital, Cleveland, OH

AST would like to thank the Pediatric Community of Practice (PCOP), in conjunction with the Infectious Disease Community of Practice (IDCOP) and Women's Health Community of Practice (WHCOP), for recommending "sexual health and monitoring recommendations for transplant recipients" as a topic for the 2019-2020 T3 series.

AST/AJT Journal Club hosted by the PCOP

AST/AJT Journal Club hosted by the PCOP

Tuesday, September 17th, 2019, from 2:00 PM ET to 3:00 PM ET • Hosted by the Pediatric Community of Practice (PCOP)

"Absence of evidence that respiratory viral infections influence pediatric lung transplantation outcomes: Results of the CTOTC-03 study."
(Am J Transplant. 2019 Jun 19. doi: 10.1111/ajt.15505.)

In this article:
[After following] 61 pediatric lung transplant recipients for 2+ years or until they met a composite primary endpoint including bronchiolitis obliterans syndrome/obliterative bronchiolitis, retransplant, or death..., findings raise the possibility that the immunologic impact of CARV following pediatric lung transplant is different than that observed in adults.

Speaker:
Stuart Sweet, MD, PhD • Washington University in St. Louis, St. Louis, MO

Moderator:
Lara Danziger-Isakov, MD, MPH • Cincinnati Children's Hospital Medical Center, Cincinnati, OH

AST/AJT Journal Clubs are free to both members and non-members. Pre-register today to support this Pediatric COP session, and please feel free to share the registration link with your colleagues!

"Absence of evidence that respiratory viral infections influence pediatric lung transplantation outcomes: Results of the CTOTC-03 study."

"Absence of evidence that respiratory viral infections influence pediatric lung transplantation outcomes: Results of the CTOTC-03 study."

Originally aired on Tuesday, September 17th, 2019, from 2:00 PM ET to 3:00 PM ET • Hosted by the Pediatric Community of Practice (PCOP)

"Absence of evidence that respiratory viral infections influence pediatric lung transplantation outcomes: Results of the CTOTC-03 study."
(Am J Transplant. 2019 Jun 19. doi: 10.1111/ajt.15505.)

Watch Video

Post-transplant lymphoproliferative disorders (PTLDs) (Tx10 Series)

"Post-transplant lymphoproliferative disorders (PTLDs)" was recorded at ATC 2018 as part of our Transplant in 10 (Tx10) educational series. Visit our Tx10 page to view the corresponding video for this session.

Speaker: Vikas R. Dharnidharka, MD, MPH, Washington University and St. Louis Children's Hospital

Date: 
Monday, August 6, 2018
Presenter: 
Vikas R. Dharnidharka, MD, MPH, Washington University and St. Louis Children's Hospital
Education Category: 

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