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Guidelines

Guidelines and opinions created or endorsed by AST and our Communities of Practice.

The American Society of Transplantation (AST) currently supports guidelines and opinions in the following categories:


 

Liver Transplantation (Adult)

This section contains liver transplant guidelines created or endorsed by the American Society of Transplantation (AST).

AASLD/AST Practice Guideline on adult liver transplantation: Candidate evaluation (Dec 2025)

Evidence-based practice guidelines on adult liver transplantation candidate evaluation. This practice guideline is available in Hepatology. 2025 Dec 17. doi: 10.1097/HEP.0000000000001644.

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AASLD/AST Practice Guideline on adult liver transplantation: Diagnosis and management of graft-related complications (Aug 2025)

Evidence-based practice guidelines on the diagnosis and management of graft-related complications. This practice guideline is available in Liver Transpl. 2025 Aug 22. doi: 10.1097/LVT.0000000000000715.

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AASLD/AST Practice Guideline on adult liver transplantation: Diagnosis and post-transplant management of non-graft-related complications (Dec 2025)

Evidence-based practice guidelines on the diagnosis and post-transplant management of non-graft-related complications. This practice guideline is available in Liver Transpl. 2025 Dec 17. doi: 10.1097/LVT.0000000000000785.

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Liver Transplantation (Pediatric)

This section contains pediatric liver transplant guidelines created or endorsed by the American Society of Transplantation (AST).

AASLD/AST/NASPGHAN Practice Guideline on Pediatric Liver Transplantation: Candidate Evaluation (June 2026)

Liver transplantation remains a critical, lifesaving treatment for children with advanced liver disease and other serious liver conditions. This practice guideline is available in Hepatology. June 22, 2026. doi: 10.1097/HEP.0000000000001805.

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AASLD AST NASPGHAN Practice Guideline on Pediatric Liver Transplantation: Post-Transplant Management (June 2026)

This Practice Guideline provides evidence-based recommendations for the comprehensive care of pediatric liver transplant recipients, from the time of transplantation through the transition to adult care. This practice guideline is available in Liver Transpl. June 22, 2026. doi: 10.1097/LVT.0000000000000939.

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Transplant Infectious Disease

This section contains transplant infectious disease guidelines created or endorsed by the American Society of Transplantation (AST).

Infectious Disease Guidelines 4th Edition (Oct 2019)

The 4th edition of the AST Infectious Disease guidelines, created by AST’s IDCOP,  reflects the evolution of the discipline, informs current clinical practice, and highlights the gaps in our knowledge and research opportunities. This edition is available in "Clinical Transplantation: Volume 33, Issue 9, Special Issue: Transplant Infectious Diseases Guidelines."

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This content was developed independently by AST and supported by a financial contribution from Sanofi