Advancing Patient Monitoring, Diagnostics, and Treatment Strategies for Transplant Precision Medicine
Advancing Patient Monitoring, Diagnostics, and Treatment Strategies for Transplant Precision Medicine
The second of three webinars from The Transplantation Society, in Collaboration with The Lancet Journal, the American Society of Transplantation, and The European Society of Organ Transplantation.
- 8:00 AM - 9:00 AM EDT
- Virtual
Overview:
Transplant medicine faces substantial challenges, as patients require lifelong immunosuppression to prevent graft rejection. Immunosuppressive regimens to date, while reasonably effective at preventing acute rejection, cause numerous health complications, compromising quality of life and patient survival. A shift towards personalised immunosuppression is needed to improve allograft health, reduce long-term adverse effects, and optimise post- transplant outcomes. This necessity has driven advancements in post-transplant monitoring and diagnostics. Innovative monitoring biomarkers and novel diagnostic modalities have been developed to advance transplant care, with many showing promise for widespread clinical implementation. With advances in artificial intelligence, algorithms have the potential to integrate multidimensional data on the immune system and allograft health, offering a comprehensive view of transplant status. This Series paper highlights the state of post-transplant immunosuppression, monitoring, and diagnostics, emphasising the transformative role of emerging innovations to personalise both allograft and patient care. Their implications could extend to xenotransplantation, further broadening their potential to redefine transplant medicine.
Speakers:
Dr. Alexandre Loupy (France)
Dr. Marta Sablik (France)
Moderators:
Dr. Camille N. Kotton, MD (TTS Education Chair; United States)
Dr. Jennifer Li (TTS Education Co-chair; Australia)
Organizer:
Dr. Peter Reese, MD, PhD (United States)
Outline:
- Understand the current challenges and limitations associated with lifelong immunosuppression in transplant recipients
- Have an overview of the recent advancements in post-transplant monitoring tools and diagnostic biomarkers, with a focus on their clinical potential for personalizing immunosuppressive regimens
- Outline future research priorities necessary to validate, standardize, and implement innovative diagnostic strategies in routine transplant clinical practice
- Outline the emerging role of artificial intelligence in transplant medicine, including how it may be used to integrate complex immunological and clinical data to enhance graft monitoring and decision-making
This webinar is hosted by the Transplantation Society, in Collaboration with The Lancet Journal, the American Society of Transplantation, and The European Society of Organ Transplantation. The full series of three webinars can be found here.
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