Blocking CCL8-CCR8–mediated early allograft inflammation improves kidney transplant function
Blocking CCL8-CCR8–mediated early allograft inflammation improves kidney transplant function
COTS invites the authors to discuss the CCL8-CCR8 axis as a promising measure to reduce early kidney allograft inflammation.
- 2:00 PM - 3:00 PM EDT
- Virtual, as part of the AST Journal Club Series.
"Blocking CCL8-CCR8–mediated early allograft inflammation improves kidney transplant function"
(J Am Soc Nephrol. 2022 Oct;33(10):1876-1890. doi: 10.1681/ASN.2022020139. Epub 2022 Aug 16.)
In this article:
In kidney transplantation, early allograft inflammation impairs long-term allograft function. However, precise mediators of early kidney allograft inflammation are unclear, making it challenging to design therapeutic interventions. [The authors found that] targeting the CCL8-CCR8 axis is a promising measure to reduce early kidney allograft inflammation.
Speaker:
- Xunrong Luo, MD, PhD, FAST • Duke University, Durham, NC
Moderator:
- Andrew Wells, PhD • University of Pennsylvania, Philadelphia, PA
Hosted by AST's Community of Transplant Scientists (COTS). All AST Journal Clubs, and featured AST/AJT Journal Clubs, are free but registration is required to attend live.
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