The AST has convened a new conference to address unmet needs in transplantation. This new initiative continues a long and successful collaboration among the various stakeholders involved in care and research surrounding solid organ transplantation. The partnership between caregivers, academic research, pharmaceutical/biotechnology companies, and regulatory authorities has advanced the science dramatically over the past several decades. We are now at the precipice of rapid transformation of these advances into clinical utilization. Thus, bringing together thought leaders from multiple disciplines to discuss, explore and advanced our thinking around the future of transplantation is the basis for establishing and convening this conference.