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Lab Monitoring

Regular lab testing is an essential part of keeping your teen healthy after their transplant. These tests help the transplant team evaluate how well the transplanted organ is working and monitor your teen’s overall health as they take on more responsibility for their care.

Why Routine Labs Matter

Routine lab testing provides important information about: 

  • How well the transplanted organ is working
  • Early signs of rejection, even before symptoms appear
  • Side effects of medications, especially the medications that prevent rejection
  • Levels of anti‑rejection medications to ensure they stay in the safest and most effective range
  • Signs of infection, which can be more serious when the immune system is suppressed
  • Other health concerns such as diabetes, electrolyte imbalances (sodium, potassium, magnesium), or anemia (low red blood cell count)
  • Your teen’s nutritional status and overall health

How Often Labs Are Needed

The frequency of lab testing varies and may change over time based on:

  • Time since transplant: Labs are needed more often early after transplant, then less frequently as your teen’s transplant health stabilizes.
  • Organ function: If rejection or other complications are being monitored, labs may be required more often.
  • Recent lab results: Concerning or abnormal results may need to be rechecked within a few days to see if they are improving or worsening.
  • Individual risks: For example, after treatment for rejection, higher immunosuppression may require closer monitoring for certain viruses or medication effects.

If you’re unsure how often labs are due, your teen’s transplant coordinator can confirm the recommended schedule.

The Nuts and Bolts of Routine Lab Testing

Where Can My Teen Get Labs?

Check with your transplant coordinator about the best option for getting your teen’s lab work done. Work with your team to find the lab that is most convenient for you. This could be a lab in your community, a hospital outpatient lab, or a preferred testing center. Making labs easy and routine increases the chances that your teen will follow through consistently. 

Many labs now offer online scheduling or apps that let you or your teen book appointments - even recurring ones like the first Monday of each month. The apps also provide reminders and instructions and offer access to test results. You can also send messages within the app if you have any questions for the lab. 

When going for labs, remind your teen to bring:

  • A form of identification (driver’s license, school photo ID)
  • Insurance information
  • A copay, if required (some bills may arrive later)

How It Works: Lab Orders

Your teen will need a current lab order from the transplant team. It’s a good idea to:

  • Confirm with the coordinator that the order on file is valid.
  • Keep a paper copy of the lab order in case the electronic version does not transmit correctly.

When Should Labs Be Drawn?

Most labs can be done at any time of day, but medication levels and fasting tests require special timing.

Immunosuppressant levels (tacrolimus, cyclosporine, sirolimus, mycophenolate) are measured by trough levels, which are the most accurate when:

  • Labs are drawn right before the next dose
  • 10–12 hours have passed since the previous dose

This timing helps the transplant team see whether your teen is taking their medication consistently and on time and that their medication is at the correct dose for their body’s needs.

Fasting Tests

If any tests require fasting, your transplant team will let you know. Always double check instructions so results are accurate.

Looking Ahead

Lab testing will remain part of your teen’s transplant care for years to come, but the good news is that it usually becomes less frequent over time, especially when your teen is doing well. Encourage your teen to:

  • Know how often their labs are due
  • Set reminders for lab appointments
  • Follow through consistently
  • Stay in communication with their transplant coordinator

Supporting your teen now helps them build the independence and confidence they’ll need to manage their transplant care – which includes routine labs - into adulthood.

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This content was developed independently by AST and supported by a financial contribution from Sanofi