- Published
Virtual Crossmatches in Real Life-New CMS Guidelines
Hosted by the AST Transplant Diagnostics Community of Practice (TxDx COP) and support by the AST Community of Transplant Scientists (COTS).
Background:
The Virtual crossmatch (VXM) assesses immunologic compatibility between recipient and potential donor through an in silico analysis of a recipient’s HLA antibody profile cross referenced against a donor’s HLA type. The goal of VXM is pre-transplant risk stratification—though there is no consensus on whether such risk assessment involves predicting the PXM result or the posttransplant outcome. Although the concept of VXM is not new, the wide application of single antigen bead assays for accurate and sensitive detection of recipient HLA antibodies and molecular methods for typing donor HLA at a higher resolution makes the routine use of VXM a reality. Implementation of VXMs allowed for expedited allocation of donor organs leading to reduced cold ischemia time without an increase in hyperacute rejection episodes. New regulations from CMS now consider VXM as a suitable alternative to cell-based crossmatches. In this webinar, we will be discussing new CMS guidelines related to VXM, and its impact on the transplant programs, HLA laboratories, and offer accepting providers standpoint.
Presenters:
- Luis G. Hidalgo, Ph.D., D(ABHI) • Director - HLA Laboratory, Associate Professor - Dept. of Surgery, University of Wisconsin – Madison
- William C. Goggins, MD, FACS, F(ACHI) • Professor of Surgery, Surgical Director Renal Transplantation, Co-Director, Transplant Immunology Laboratory, Indiana University School of Medicine
Moderators:
- Qingyong Xu, Ph.D., D(ABHI), F(ACHI) • Co-Director, Histocompatibility Laboratory, University of Pittsburgh Medical Center (UPMC), Assistant Professor, Pathology and Thomas E. Starzl Transplantation Institute, University of Pittsburgh
- Yousuf Kyeso, MD, FASN • Assistant Professor of Medicine, Transplant Nephrology, University of Chicago Medicine
This webinar is hosted by the AST Transplant Diagnostics Community of Practice (TxDx COP), support by the AST Community of Transplant Scientists (COTS), and approved by AST for expanded marketing by the AST Education Committee.
Advertisements
