Program | American Society of Transplantation

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Title

Program

Immunity and Inflammation:
Engineering Cell, Gene and Drug Therapies
Program

Thursday, February 5

5:00 - 7:00 pm	Session 1: Keynote Presentation: Promises, Promises Moderators: Anil Chandraker, MD, FRCP, Brigham and Women's Hospital and Jonathan Maltzman, MD, PhD, University of Pennsylvania UAN 0530-9999-15-005-L01-P: this is a knowledge-based activity *This 120-minute session is approved for continuing education credit. See CME packet for full details.*
5:00 pm	Tregs: What is the Promise of Cell Therapy? What's Around the Corner? What Will You See in Your Lifetime? Kathryn Wood, DPhil, University of Oxford Questions and Discussion
6:00 pm	Provacative Panel Discussion Moderator: Roslyn Mannon, MD, University of Alabama at Birmingham Panel: James Allan, MD, MBA, Massachusetts General Hospital John Friedewald, MD, Northwestern University Jason Wertheim, MD, PhD, Northwestern Kathryn Wood, DPhil, University of Oxford
7:00 - 8:30 pm	Welcome Networking Reception

Friday, February 6

7:15 am - 8:15 am	Breakfast Satellite Symposium presented by Transplant Genomics Inc. This is not an official function of the CEOT meeting and is not endorsed by the AST. Towards Clinical Use of Genomic Biomarkers in Transplantation Strategic Use of Biomarkers to Improve Patient Outcomes Michael Abecassis, MD, MBA, Northwestern University Comprehensive Transplant Center The Promise of Biomarkers in Transplantation - Are We There Yet? John Friedewald, MD, Northwestern University Comprehensive Transplant Center
8:15 am - 8:30 am	Break
8:30 am - 10:00 am	Session 2: Promising New Drugs in Others Fields: How Do You Address Immune Response in Your Area? Can We Use These in Transplant? Moderators: Kenneth Newell, MD, PhD, Emory University and Parmjeet Randhawa, MD, University of Pittsburgh Medical Center UAN 0530-9999-15-006-L01-P: this is a knowledge-based activity *This 90-minute session is approved for continuing education credit. See CME packet for full details.*

8:30 am	Novel Approaches to Immune Monitoring in Rheumatology PJ Utz, MD, Stanford University School of Medicine
9:00 am	Identifying Therapeutic Targets by Process Rather Than System: Examples from Inflammatory Bowel Disease Peter Ernst, DVM, PhD, University of California, San Diego
9:30 am	Mechanism-based Cancer Immunotherapy Thomas Gajewski, MD, PhD, University of Chicago
10:00 am - 10:30 am	Break
10:30 am - 11:30 am	Session 3: A New Beginning for Drugs in Transplant Moderators: Rita Alloway, PharmD, University of Cincinnati and Robert Gaston, MD, University of Alabama at Birmingham This session is NOT approved for continuing education credit.
10:30 am	Adding Value: The Approach to Repositioning Drugs Daniel Curran, MD, Takeda Pharmaceutical Company

11:00 am	Academia Approach to Discovering New Drugs Patrick Griffin, PhD, The Scripps Research Institute
11:30 am - 12:30 pm	Session 4: Moderated Discussion Moderators: Anthony Jevnikar, MD, London Health Sciences Centre and Michael Mengel, MD, University of Alberta This session is NOT approved for continuing education credit. Perspectives: Herwig-Ulf Meier-Kriesche, MD, Bristol-Myers Squibb Roslyn Mannon, MD, University of Alabama at Birmingham E. Steven Woodle, MD, University of Cincinnati Rita Alloway, PharmD, University of Cincinnati
	What are the barriers to drug development for transplantation?
	How can industry, academics, clinicians and government work together to define the problems and solutions to drug development?
	Will the model for funding transplantation research change in the future?
	How can we involve government, industry and academia to appropriately design a repositioning study that could lead to a transplant indication?

12:30 pm - 5:30 pm

Meeting Recess/Networking

5:30 pm - 7:00 pm	Session 5: Critical Review of Cell Therapies Moderators: Ronald Gill, PhD, University of Colorado Denver and Jonathan Maltzman, MD, PhD, University of Pennsylvania *This session is NOT approved for continuing education credit.*
5:30 pm	The Many Colors of Regulatory Cells: Not Just Your Father's Suppressor Cells Jonathan Maltzman, MD, PhD, University of Pennsylvania
5:45 pm	Using Adoptive Therapy of Tregs Kathryn Wood, DPhil, University of Oxford
6:15 pm	The Potential of Innate Immune Cells Angus Thomson, PhD, DSc, University of Pittsburgh School of Medicine
6:45 pm	How Do You Develop a Cellular Therapy That is Commercially Viable? Nancy Krieger, MD, Novartis Pharmaceuticals Corporation
7:15 pm - 8:00 pm	Rapid Fire Abstracts This session is NOT approved for continuing education credits.
8:00 pm - 9:30 pm	Distinguished Faculty Poster Review and Dinner Reception Attendees are welcome to follow one of the groups of distinguished faculty as they engage presenters in discussion, offering feedback and suggestions.

Saturday, February 7

7:15 am - 8:15 am	Breakfast
8:15 am - 8:30 am	Break
8:30 am - 10:30 am	Session 6: Whatever Happened to Gene Therapy? Moderators: Jamil Azzi, MD, Brigham and Women's Hospital and Angus Thomson, PhD, DSc, University of Pittsburgh School of Medicine UAN 0530-9999-15-007-L01-P: this is a knowledge-based activity *This 120-minute session is approved for continuing education credit. See CME packet for full details.*
8:30 am	Novel Approaches to Modifying the Genome A. Joseph Tector, III, MD, PhD, Indiana University School of Medicine
9:10 am	From Bench to Bedside in the Valley of Death: How Do You Translate from Research to Clinic? Malcom Brenner, MD, PhD, Baylor College of Medicine

9:50 am	Ex-Vivo Organ Repair Shaf Keshavjee, MD, Toronto General Hospital
10:30 am - 11:00 am	Break
11:00 am - 1:00 pm	Session 7: Engineering Organ Repair and Regeneration Moderators: Anil Chandraker, MD, FRCP, Brigham and Women's Hospital and Jonathan Maltzman, MD, PhD, University of Pennsylvania UAN 0530-9999-15-008-L01-P: this is a knowledge-based activity *This 120-minute session is approved for continuing education credit. See CME packet for full details.*
11:00 am	Novel Therapeutic Strategies for Regenerative Medicine Andrew McMahon, PhD, University of Southern California
11:30 am	Lab-made Hepatocytes Holger Willenbring, MD, PhD, University of California, San Francisco
12:00 pm	Differentiation of Stem Cells in 3D Jason Wertheim, MD, PhD, Northwestern University
12:30 pm	3D Liver Tissue Printing Keith Murphy, Organovo

1:00 pm - 5:00 pm

Meeting Recess/Networking

5:00 pm - 6:30 pm	Session 8: Organogenesis and Regenerative Medicine Moderators: James Allan, MD, MBA, Massachusetts General Hospital and Jason Wertheim, MD, PhD, Northwestern University UAN 0530-9999-15-009-L01-P: this is a knowledge-based activity *This 90-minute session is approved for continuing education credit. See CME packet for full details.*
5:00 pm	Tissue Engineering of Urological Structures: Accomplishments and Future Challenges for Clinical Translation Shay Soker, PhD, Wake Forest Institute for Regenerative Medicine
5:30 pm	Liver Tissue Engineering Alejandro Soto-Gutierrez, MD, PhD, University of Pittsburgh
6:00 pm	The Implantable Bioartificial Kidney Shuvo Roy, PhD, University of California, San Francisco
6:30 pm - 7:30 pm	The Unplenary Back to Basics: It's All About Tolerance Jeffrey Bluestone, PhD, University of California, San Francisco UAN 0530-9999-15-010-L01-P: this is a knowledge-based activity This 60-minute session is approved for continuing education credit. See CME packet for full details.
7:30 pm	Closing Dinner Event