2018 CEoT Program

Click Here to View The Full CEoT Program

*Inclusive of Abstract Information

Thursday, February 8, 2018

1:45 PM                     

Welcome Remarks

Anil Chandraker, MD, FASN, FAST, FRCP, Brigham and Women’s Hospital         

Kenneth Newell, MD, PhD, FAST, Emory University                                               


2:00 - 3:30 PM          

Session 1: Xenotransplantation, Are We Finally Ready? A Field, Challenging and Challenged by Regulation

Moderators: Andrew Adams, MD, PhD                                             

James Allan, MD, MBA, FAST                                                

2:05 PM      We Are Ready for Prime-Time, Invest Today!

                   Joseph Tector, MD, PhD

2:30 PM      We’re Close but We Need to Consider the Following Issues Before Sinking in Your Money

                    Andrew Adams, MD, PhD

2:55 PM      Hold on Here, Your Money Might be Better Invested Somewhere Else

                    Ronald Gill, PhD



4:00 - 5:30 PM          

Session 2: Defining True Innovation - Lessons from Transplantation’s Past

Moderators: Kenneth Newell, MD, PhD, FAST                                 

Anil Chandraker, MD, FASN, FAST, FRCP

4:05 PM      Innovation in Surgical Technique – Living Donor Liver Transplantation

                    Jean Emond, MD 

4:20 PM      Innovation in Immunosuppression

                    Arthur Matas, MD

4:35 PM      Innovation in Organ Donation

                   Darren Malinoski, MD

4:50 PM      Innovation in Regulatory Framework – the National Academy of Science Study

                   Alexandra Glazier, JD, MPH 


5:45 - 7:00

Poster and Welcome Reception


Friday, February 9, 2018

7:30 AM 



8:00 – 10:00 AM      

Session 3: Option One, OPTN/UNOS Policies and Organ Utilization - Necessary and Beneficial, or Obstacles to Growth & Innovation? *                                        

Moderator: Richard Formica, MD

Deceased Donors Starting Living Donor Chains

8:00 AM    The Rationale and Potential Benefit for Using Deceased Donors to Start KPD Chains

                  Nicole Turgeon, MD 

8:10 AM    The Legal and Regulatory Issues Posed by Using Deceased Donors to Start KPD Chains

                  David Klassen, MD 

New Paradigms for Allocating Organs - When Should Utility Override Equity?

8:30 AM    European Perspective on Expedited Allocation

                   Axel Rahmel, PhD

8:40 AM    Novel Ideas for Expedited Allocation

                    Darren Stewart, MS

8:50 AM    Proposing a New Paradigm -Less Choice, More Allocation

                    Jesse Schold, PhD, M. Stat, M.Ed

Re-Envisioning OPTN/UNOS

9:20 AM    People and Data

                   Brian Shepard, MBA 

9:30 AM    Changing OPTN/UNOS Implementation Policies and Practices: Supporting Innovation in a Structured Environment

                   Richard Formica, MD 

9:40 AM    HRSA Role as a Force Innovation in Transplantation

                    Melissa Greenwald, MD 

9:50 AM    UNOS Labs: Leveraging Behavioral Science to Improve Organ Allocation

                    Darren Stewart, MS 


8:00 – 10:00 AM      

Session 3: Option Two, Heart Track: Rise of the Machines - Regulatory Considerations in MCS Therapy*

Moderators: Liviu Klein, MD                                                  

Rondalyn Ford-McLean, MD

8:00 AM    LVADs as Destination Therapy- When Best Practice Criteria Meets the Real World

                   Farooq Sheikh, MD

8:15 AM    The Total Artificial Heart – What Metrics Should be Met for Standard Use? For Future Technology

                    Francisco Arabia, MD

8:30 AM    ECMO and Short Term Support -Utilization Guidelines and Impact of the New Heart Allocation Sytem

                   Jeffrey Teuteberg, MD 

8:45 AM    MCS Complications-Understanding Risks and Rewards in the Context of Appropriate Use Benchmarks

                    Liviu Klein, MD

9:00 AM    DEBATE:

                    Innovation in MCS Technology is Helped by Regulation

                     Palak Shah, MD

                     Innovation in MCS Technology is Hindered by Regulation

                      O.H. Frazier, MD

9:30 AM    The Cost of Success vs the Cost of Failure – Financial Considerations in Advancing Innovation

                     Simon Maltais, MD


8:00 – 10:00 AM      

Session 3: Option Three, Lung Track: The Evolution of Lung Support Devices - Regulatory Considerations in Lung Transplantation*

Moderators: Sangeeta Bhorade, MD                        

Christopher Wigfield, MD

8:00 AM    DEBATE: ECMO as a Bridge to Transplant Should be Exempt from 1 Year Mortality Outcomes in Lung Transplant

- Con

Charles Hoopes, MD

– Pro

Duane Davis, MD           

8:40 AM    DEBATE: Ex Vivo Lung Perfusion is an Essential Tool for Donor Optimization

 – Pro

Shaf Keshavjee, MD

– Con

Thomas Egan, MD, MSc

9:20 AM    The Regulatory Imperative – Impact on the Practice of Lung Transplant

                    Christopher Wigfield, MD

9:35 AM    Regulatory Realities – Redefining Benefit of Lung Transplant in the Current Era

                   Gundeep Dhillon, MD, MS



10:15 – 12:15 PM     Session 5: Option One, Program-Specific Reports: Past, Present and Future. Where do we go from here?*

Moderators: Jesse Schold, PhD, M. Stat, M. Ed                          

John Gill, MD, MS

10:15 AM      The Past

                     Bertram Kasiske, MD 

10:45 AM      The Present

                     Jon Snyder, PhD

11:15 AM      The Future – What Would an Ideal Report Card Look Like?

                     Melissa Greenwald, MD

Jon Friedman, MD, FAST

Luke Preczewski

Jesse Schold, PhD, M.Stat, M. Ed


10:15 – 12:15 PM     

Session 5: Option Two, Heart Track: Alternatives to Heart Transplantation - Overcoming Barriers to Success*

Moderators: Joren Madsen, MD                                 

Shelley Hall, MD

10:15 AM      DCD Heart Donation – Understanding the Regulatory and Ethical Issues

                    Val Jeevanandum, MD

10:35 AM      Xenotransplantation – Promise and Pragmatism

                    Robin Pierson, MD

10:55 AM      Whole Organ Engineering – Science and Sensibility

                    Doris Taylor, MD 

11:15 AM      Stem Cell Therapy – Engineering Process

                    Lawrence Czer, MD 

11:35 AM      Ex Vivo Heart Perfusion – Removing Time and Distance Barriers

                    Abbas Ardehali, MD


10:15 – 12:15 PM        

Session 5: Option Three, Lung Track: Trials, Tribulations and Triumphs in Lung Transplant Innovations

Moderators: Martin Zamora, MD                                           

Duane Davis, MD

10:15 AM      Cell Free DNA and Other Immune Monitoring Techniques in Lung Transplantation – Are We There Yet?

                    David Neujhar, MD

10:35 AM      Controlled Donation After Determination of Circulatory Death (cDCDD) – Improving Yield

                    Michael Smith, MD 

10:55 AM      Xeno Lung Transplantation – The Path Forward

                    Agnes Azimzadeh, PhD 

11:15 AM      Extracorporeal Lung Support – A Bridge Too Far?

                   Jonathan D’Cunha, MD

11:35 AM      The Artificial Lung – Can it be Realized?

                    Williams Federspiel, PhD


12:15 – 1:00 PM Congressional Keynote Speaker

The Honorable Congresswoman Jaime Herrera Beutler (R-WA)
U.S. House of Representatives


1:15 – 2:30 PM

Satellite Symposium presented by CareDx, Inc                                          

This is not an official function of the CEoT meeting and is not endorsed by the AST.


2:15 PM          Inaugural AST Innovation Award Presentation

                        Anil Chandraker, MD, FASN, FAST, FRCP

This new award was created to showcase a project or program that exemplifies the spirit of innovation on which transplantation was founded. Join us to honor the recipient, and hear a brief presentation on the program's successful, outside-the-box approach that earned it the first Innovation Award.


2:45 PM    Break


3:00 PM    Advocacy


3:30 – 4:00 PM  Congressional Keynote Speaker                             

The Honorable Congressman Eric Swalwell (D-CA)

U.S. House of Representatives


Saturday, February 10, 2018

7:00 – 8:15 AM          

Satellite Symposium presented by One Lambda Inc., A Thermo Fischer Scientific Brand 

This is not an official function of the CEoT meeting and is not endorsed by the AST.


8:15 AM                     



8:30 – 10:00 AM       

Session 6: Option One, Clinical Therapeutics to Improve Patient Outcomes - The Tribulations of Trials in Transplantation*

Moderator: Roy Bloom, MD            

Roslyn Mannon, MD

8:30 AM      Tracking Transplant Treatment Trials - Where Are We and What are the Barriers

                    Roy Bloom, MD 

9:00 AM      Victims of Success- Do We Still Need Clinical Trials and If So, What are Our Needs

                   Robert Gaston, MD 

9:30 AM      Can We Get There? Re-Thinking Clinical Trial Design

                   Jesse Schold, PhD 

9:45 AM      Panel Discussion with:

                   Renata Albrecht, MD

                   Peter Maag, PhD

                   Kevin Campbell 


8:30 – 10:00 AM       

Session 6: Option Two, Case Studies in Thoracic Transplantation - Integrating Innovation

Moderators: Jon Kobashigawa, MD            

Nicholas Braus, MD

8:30 AM      Extended Criteria Heart vs Destination LVAD

                    Liviu Klein, MD and Mahwash Kassi, MD

8:45 AM      Hep-C Heart and Lung Transplantation

                    Shelley Hall, MD and Luke Cunningham, MD 

9:00 AM      Ex Vivo Lung

                    Jonathan D’Cunha, MD and Lara Schaheen, MD 

9:15 AM      Ex Vivo Heart

                   Jason Smith, MD and Tori Lennox, MD 

9:30 AM      DCD Lung

                    Martin Zamora and Nicholas Braus, MD 


10:00 AM 



10:30 – 12:00 PM     

Session 7: Approaches to Facilitating the Approval of New Therapeutics in Transplantation *

Moderators: Kenneth Newell, MD, PhD, FAST

Anil Chandraker, MD, FASN, FAST, FRCP

10:30 AM    Low and Not So Low Hanging Fruit – New Study Endpoints and Biomarkers

                    Ulf Meier-Kriesche, MD 

10:50 AM    Regulatory Approaches to Facilitating the Use of Therapies Approved for Other Indications in Transplantation

                   Mark Stegall, MD

11:10 AM    PROs – New Opportunities to Measure Something That Matters to Patients

                    Stephen Joel Coons, PhD 


12:15 PM – 1:30 PM 



1:30 – 3:00 PM          

Session 8: Out of Synch - How Can Factors That Drive OPO and Transplant Center Practice be Aligned to Increase the Number of Patients Who Receive a Transplant*

Moderators: John Gill, MD, MS                    

Dave Foley, MD, FACS

1:30 PM      Critique of the Current OPO Performance Metrics and Proposed Improvement

                    Characteristics of an Optimal OPO Metric

                     David Goldberg, MD, MSCE

                     My Pick for A New OPO Metric

                     Elling Eidbo, MBA

1:45 PM      Regulatory and Financial Considerations That Impact OPO Performance – What Changes Would Increase Transplantation?

                    Kevin O’Connor, MS, PA

2:00 PM      Regulatory and Financial Considerations That Impact Transplant Center Practice – What Changes Would Increase Transplantation?

                    Matthew Cooper, MD

2:15 PM      Reaction to the Proposed Solutions

                    Brian Shepard, MBA

2:30 PM      Panel Discussion with:

                     Jon Snyder, PhD


3:00 – 3:30 PM          

Session 9: Summary Heart/Lung Track     

Jon Kobashigawa, MD                       
Sangeeta Bhorade, MD 


3:30 - 4:00 PM            

Session 10: Summary and Next Steps

Anil Chandraker, MD, FASN, FAST, FRCP                       
Kenneth Newell, MD, PhD, FAST 


4:00 – 4:15 PM          


Anil Chandraker, MD, FASN, FAST, FRCP
Kenneth Newell,


5:00 PM                     

Poolside Reception