Focal nodular hyperplasia of the liver in children after hematopoietic stem cell transplantationPediatric Transplantation (login required)
FNH is a non-malignant neoplasia of the liver rarely described in children. A significant percentage of the pediatric cases have been reported in patients with a history of malignant disease treated with chemo-radiation therapy and in children who were given HSCT. Little is known about the pathogenesis of FNH in transplanted children, but many risk factors linked to the HSCT procedure have been hypothesized. The detection of hepatic nodules, particularly... Read More...
In a press release sent out yesterday, Representative Lois Capps (CA-24) applauded the House Energy and Commerce Committee's passage of the HOPE Act (H.R. 698, the HIV Organ Policy Equity Act), a bill she authored that would create a science-based path for medical research to proceed on the feasibility, effectiveness and safety of HIV-positive to HIV-positive organ transplants.
AST President, Dr. Daniel Salomon, was quoted in the press release commending the work of Congresswoman Capps to introduce the HOPE Act and for her work in developing the new policy. "On behalf of the American Society... Read More...
Gene test may ID kidney rejectionMedPage Today (login required)
A urine-derived three-gene signature showed potential for noninvasive discrimination of kidney grafts that are being rejected from those that are not, a study of almost 500 kidney recipients showed. Read more.
Donor-specific antibodies: Can they predict C4d deposition in pediatric heart recipients?Pediatric Transplantation (login required)
There is limited evidence regarding the utility of circulating DSA in surveillance for... Read More...
The AST recently commented on the following OPTN policy proposals:
Proposal to Redefine the Role of the Vice-President of the Board of Directors
Propoal to Add Serum Sodium to the MELD Score
Proposed Changed to the OPTN Bylaws Governing Histocompatibility Labs
Proposed Update to the HLA Equivalency Tables in Appendix 3A
Proposal to Clarify Requirements for Independent Donor Advocates (IDA) at Living Kidney Donor Recovery Center
Proposal to Change Pediatric Heart Allocation Policy
Click here to read AST's... Read More...
The national program for deceased organ donation in ChinaTransplantation (login required)
China has developed a new national program for deceased-organ donation to address the need for organ transplantation in the country. The program adheres to the World Health Organization guiding principles, is compliant with the Declaration of Istanbul, and respects the cultural and social values of the Chinese people. The experience of pilot trials conducted between 2010 and 2012 was evaluated to generate a comprehensive design of a national program of organ donation and transplantation for... Read More...
AST's Timely Topics in Transplantation
webinar series is available free to members 24/7 online Webinars include "DSA: New Concerns and New Therapies," "New Strategies in Hepatitis Management," and "Meeting the Challenges of Resistance." The AST's Business of Transplantation
live webinar series has concluded, but all eight webinars are available in archive format.
Are we on the right track with new drugs and biologics? Have the targets changed? Where can we really impact outcomes with "technology-omics?" The time has come to integrate our strategies, therapies and technology, and critically assess their merits as we face the enormous task of extending transplant survival. Save the date for the 2014 AST Cutting Edge of Transplantation
where expert clinicians, leading diagnosticians, and world class scientists will address this enormous challenge together with an engaged audience.
When: Feb. 13-16,... Read More...
American Society of Transplantation Board Member Provides Expert Testimony to
House Energy & Commerce Committee in Support of Key Immunosuppressive
Drug Coverage Legislation
Dr. Larry Melton of Baylor University Medical Center offers insight to Congress as it examines reforms to improve the Medicare Part B Drug Program
WASHINGTON, DC, June 28, 2013 - The American Society of Transplantation (AST), an international organization of transplant professionals dedicated to advancing the field of transplantation, today announced that AST Board Member Dr. Larry Melton has offered key testimony... Read More...
* CALL TO ACTION - Contact Your House Member *
Last night the U.S. Senate passed the HIV Organ Policy Equity (HOPE) Act by a unanimous vote. As you know, the American Society of Transplantation (AST) and Washington, DC office have advocated strongly for this bill on Capitol Hill. The Society was most instrumental in securing key Majority support for the bill in the U.S. House of Representatives and has been working collectively with all stakeholders to build bipartisan and bicameral support for the bill. AST is also hosting a meeting of all the HOPE Act stakeholders next week in our DC... Read More...
A case for bariatric surgery among obese renal transplant candidatesBy Maria Frisch
Approximately 1 in 3 U.S. adults are obese or have a body mass index of 30 or higher. England and Canada aren't far behind at every 1 in 4. This is unfortunate, given the common association between obesity and excess morbidity and mortality. This association is particularly true in renal transplant surgery. Thus, consideration of presurgical bariatric surgery may be warranted in cases where prescribed dietary therapy and physical activity has failed.... Read More...