Full press release below
November 4, 2013
Brussels, Belgium - - - Kidney Disease: Improving Global Outcomes (KDIGO) has announced the publication of a new evidence-based Clinical Practice Guideline making recommendations on treatment of dyslipidemia in chronic kidney disease (CKD). The guideline will appear in the November issue of Kidney International Supplements.
The Clinical Practice Guideline for Lipid Management in Chronic Kidney Disease
is KDIGO’s ninth global... Read More...
Brian M. Shepard has been selected as Chief Executive Officer of UNOS (United Network for Organ Sharing). UNOS matches donated organs with transplant candidates nationwide and manages the national transplant database through contract with the U.S. Department of Health and Human Services.
As Chief Executive Officer, Shepard directs the efforts of more than 300 UNOS staff to ensure that the nation's transplant network efficiently and fairly serves the needs of transplant candidates and recipients, living donors and donor family members, and transplant professionals. He reports to the UNOS... Read More...
Attention AST Members: It's time to renew your membership for 2014. Please log in to the AST website
today to pay your dues online. If you have forgotten your login credentials, simply click the "Forgot Password" link to have the information emailed to you. Contact the AST office at info@myAST.org
with any questions.
Important Notice: In order to receive the member-discounted registration rate for the 2014 World Transplant Congress (WTC) in San Francisco, your dues must be paid by March 1, 2014.
On September 24th & 25th, AST's Public Policy Committee descended on Capitol Hill and met with more than a dozen Members of Congress in the U.S. Senate and House of Representatives. A majority of the meetings were with the actual Senators and Congressmen themselves.
The two primary purposes for AST's visits with members of Congress was to: 1) garner further support for federal funding of NIH and medical research; as well as 2) strengthen support and cosponsors for the Transplant Patient Immunosuppressive Drug Coverage for Kidney Patients Act of 2013. The Society's leaders also discussed... Read More...
Renal Ischemia-Reperfusion Injury Amplifies the Humoral Immune Response
Journal of the American Society of Nephrology
Renal transplant recipients who experience delayed graft function have increased risks of rejection and long-term graft failure. Ischemic damage is the most common cause of delayed graft function, and although it is known that tissue inflammation accompanies renal ischemia, it is unknown whether renal ischemia affects the production of antibodies by B lymphocytes, which may lead to chronic humoral rejection and allograft failure.... Read More...
Effective Oct. 1, a new policy (3.1.14) created to define the PHS Guideline will allow members to use either the 1994 or the 2013 version. It will also require members to specify which version they are using in the donor highlights section of DonorNet. Click here
for more information, or see a comparison of the guidelines.
The AST recently provided the OPTN with comments on the plain language policy rewrite. View the comments here
This extensive three-day course focuses on non-clinical, early clinical, and phase 3 studies, issues in the design and analysis of trials, safety and ethical considerations and FDA's regulatory requirements related to the performance and evaluation of clinical studies. Attendees have the unique opportunity of hearing directly from FDA’s nationally renowned experts on issues critical to successful clinical research. The course is designed for physicians, nurses, pharmacists and other health care professionals involved in clinical trials.
November 12-14, 2013
College Park, MD
For more... Read More...
Repopulation of the immunosuppressed retrorsine-treated infant rat liver with human hepatocytes
Xenotransplantation (login required)
Humanized chimeric mice have been generated by transplanting h-hepatocytes into the livers of the diseased-liver transgenic mouse model with immunodeficient background. These mice with livers mostly replaced by human (h) hepatocytes have been proved to be useful for research on drug metabolism and toxicity and on intrahepatic pathogens such as hepatitis. However, their small body size prohibited collecting sufficient biological samples and made surgical... Read More...
When: Monday, Sept. 16,1-5:30 p.m.; and Tuesday, Sept. 17, 8 a.m.-3:30 p.m.
Where: Sheraton Pentagon City Hotel, 900 South Orme Street, Arlington, VA
This meeting allows members of the DTCP to come together to identify challenges that the community has identified related to donor management research. Participants will work toward consensus on issues related to donors, identify issues related to informed consent in the recipient, recognize and address informed consent issues regarding the effect of research on... Read More...