Basic science

Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients

Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients

Recorded live on Tuesday, November 16, 2021 • Hosted by AST's Community of Transplant Scientists (COTS)

"Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients"
(Sci Immunol. 2021 Jun 15;6(60):eabj1031. doi: 10.1126/sciimmunol.abj1031.)

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AST/AJT Journal Club on Recipient sex and estradiol levels and transplant outcomes

AST/AJT Journal Club on Recipient sex and estradiol levels and transplant outcomes

"Recipient sex and estradiol levels affect transplant outcomes in an age-specific fashion"
(Am J Transplant. 2021 May 28. doi: 10.1111/ajt.16611. Online ahead of print.)

Panelists:
- Jasper Iske, MD • Brigham and Women`s Hospital, Boston, MA
- Friederike Martin, MD • Charité-Medical University, Berlin, Germany
- Stefan Tullius, MD, PhD • Brigham and Women`s Hospital, Boston, MA

Moderators:
- Amandeep Bajwa, PhD • University of Tennessee Health Science Center, Memphis, TN
- Dianne McKay, MD, FAST • Scripps Clinic, San Diego, CA

AST/AJT Journal Clubs are free, but registration is required.

Recipient sex and estradiol levels affect transplant outcomes in an age-specific fashion

Recipient sex and estradiol levels affect transplant outcomes in an age-specific fashion

Recorded live on Friday, August 6, 2021 • Hosted jointly by AST's Community of Transplant Scientists (COTS) and Women's Health Community of Practice (WHCOP)

"Recipient sex and estradiol levels affect transplant outcomes in an age-specific fashion"
(Am J Transplant. 2021 May 28. doi: 10.1111/ajt.16611. Online ahead of print.)

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AST/AJT Journal Club on Transitional B Cell Cytokines & Renal Allograft Outcomes

AST/AJT Journal Club on Transitional B Cell Cytokines & Renal Allograft Outcomes

"Transitional B cell cytokines predict renal allograft outcomes"
(Sci Transl Med. 2021 Feb 24;13(582):eabe4929. doi: 10.1126/scitranslmed.abe4929.)

Speaker:
- Aravind Cherukuri, MBBS, PhD, MRCP • University of Pittsburgh, Pittsburgh, PA

Moderators:
- Aman Bajwa, PhD • University of Tennessee Health Science Center, Memphis, TN
- Olivia Martinez, PhD • Stanford University, Stanford, CA

Discussant:
- David Rothstein, MD • University of Pittsburgh, Pittsburgh, PA

AST/AJT Journal Clubs are free, but registration is required.

Transitional B cell cytokines predict renal allograft outcomes

AST/AJT Journal Club on Mixed Chimerism and Acceptance of Kidney Transplants (Hosted by COTS)

AST/AJT Journal Club on Mixed Chimerism and Acceptance of Kidney Transplants (Hosted by COTS)

Join us live on Tuesday, March 30, 2020, from 2:00 PM ET to 3:00 PM ET • Hosted by the Community of Transplant Scientists (COTS)

"Mixed Chimerism and Acceptance of Kidney Transplants after Immunosuppressive Drug Withdrawal"
(Science Translational Medicine 29 Jan 2020:Vol. 12, Issue 528, eaax8863; DOI: 10.1126/scitranslmed.aax8863)

Speakers:
- Stephan Busque, MD; Stanford University School of Medicine, Stanford, CA
- Samuel Strober, MD; Stanford University School of Medicine, Stanford, CA

Moderator:
- Aman Bajwa, PhD; University of Tennessee Health Science Center, Memphis, TN

AST/AJT Journal Clubs are free, but registration is required.

Mixed Chimerism and Acceptance of Kidney Transplants after Immunosuppressive Drug Withdrawal

Mixed Chimerism and Acceptance of Kidney Transplants after Immunosuppressive Drug Withdrawal

Recorded live on Tuesday, March 30, 2021, from 2:00 PM ET to 3:00 PM ET • Hosted by the Community of Transplant Scientists (COTS)

"Mixed Chimerism and Acceptance of Kidney Transplants after Immunosuppressive Drug Withdrawal"
(Science Translational Medicine 29 Jan 2020:Vol. 12, Issue 528, eaax8863; DOI: 10.1126/scitranslmed.aax8863)

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T3 Webinar: "Biomarkers and Gene Expression Profiling in Transplantation"

T3 Webinar: "Biomarkers and Gene Expression Profiling in Transplantation"

Speakers:

  • Benjamin Adam, MD, FRCPC • Assistant Professor of Pathology, University of Alberta, Edmonton, AB
  • Gaurav Gupta, MD • Associate Professor; Medical Director of Kidney Transplantation, Virginia Commonwealth University, Richmond, VA
  • Manikkam Suthanthiran, MD • Stanton Griffis Distinguished Professor of Medicine - Weill Cornell Medical College, Cornell University, New York, NY

Moderator:

  • Minnie Sarwal, MD, PhD, FRCP, DCH • Professor, Surgery; Director, Kidney-Pancreas Transplant, UCSF, San Francisco, CA
- - - - -

AST would like to thank the Community of Transplant Scientists (COTS) and the Transplant Diagnostics Community of Practice (TxDx COP) for recommending topics related to "gene expression" and "biomarkers" for the 2020-2021 T3 series. These suggestions directly contributed to the creation of the "Biomarkers and gene expression profiling in transplantation" webinar. Learn more about AST's COPs at www.myast.org/cops.

Biomarkers and Gene Expression Profiling in Transplantation

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For "NanoString Technologies for Intragraft Gene Expression" - after participating in this webinar, the attendee will be able to:

  1. Recognize current methodologies and clinical indications for intragraft gene expression testing.
  2. Describe new opportunities afforded by emerging FFPE-based intragraft gene expression technologies.

For "Donor-Derived Cell-Free DNA" - after participating in this webinar, the attendee will be able to:

Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells

Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells

Recorded live on Tuesday, November 24, 2020, from 2:00 PM ET to 3:00 PM ET • Hosted by the AST Community of Transplant Scientists

"Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells."
(Science Translational Medicine; 19 Aug 2020: Vol. 12, Issue 557, eaaz3866; DOI: 10.1126/scitranslmed.aaz3866)

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