Thursday, April 6th, 2023, from 2:00 PM ET to 3:00 PM ET • Hosted by AST's Community of Transplant Scientists (COTS)
"Blocking CCL8-CCR8-Mediated Early Allograft Inflammation Improves Kidney Transplant Function"
(J Am Soc Nephrol. 2022 Oct;33(10):1876-1890. doi: 10.1681/ASN.2022020139. Epub 2022 Aug 16.)
In this article:
In kidney transplantation, early allograft inflammation impairs long-term allograft function. However, precise mediators of early kidney allograft inflammation are unclear, making it challenging to design therapeutic interventions. [The authors found that] targeting the CCL8-CCR8 axis is a promising measure to reduce early kidney allograft inflammation.
- Xunrong Luo, MD, PhD, FAST • Duke University, Durham, NC
- Andrew Wells, PhD • University of Pennsylvania, Philadelphia, PA
All AST Journal Clubs, and featured AST/AJT Journal Clubs, are free but registration is required to attend live.